Advantages of Using 96 Tomtec SPE Tips over 96-Well SPE Plate

  1. Independent SPE for each tip (concurrent 96 mini SPE columns)

  2. Positive pressure liquid flow for tips vs. negative pressure vacuum flow for 96-well SPE plate

    • Less variable results
    • Higher recovery and loading capacity due to recirculation
    • Better liquid flow control of critical loading and elution steps
    • No differential vacuum treatment
    • No need to cover unused wells
    • Easy to expand to 384 SPE

  3. Less expensive to operate

    • No waste of unused SPE wells
    • Low consumption of solvents, reagents, and tips
    • Low solvent disposal
    • No need to use vacuum manifold, in-house vacuum, and centrifuge

  4. Low cross-well contamination and carry-over

    • Liquid flow is confined inside tips and collection plate vs. close proximity between well-to-well in SPE plate

  5. Very short run time per assay

    • Fewer operational steps
    • Continuous SPE operation

  6. Easy detection and possible recovery of clogged samples

    • Easy and clear to observe each tip's SPE process

  7. Great for animal samples with low volume

    • Elution with low volume ready for injection (elute and shot technique)

  8. Fast method development

    • Use Combination of different packings on a tip rack for quick method development


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